Gilva Therapeutics, INC.

NEWS

INTRODUCTION

Gilva is a biopharmaceutical company focused on the development of small molecule drugs for unmet medical needs, especially in rare diseases.
Gilva has a robust drug discovery and development platform. This platform effectively optimizes the efficacy, druggability or safety of drugs based on the structure-activity relationship (SAR). Gilva also has a team with extensive experience in drug development, which can improve the efficiency of drug discovery and reduce development risks.

People work together, keep an eye on the future, and bring ideas to life People work together, keep an eye on the future, and bring ideas to life

PIPELINE

GV-100

GV-100 is an oral selective HDAC6 inhibitor. HDAC6 interacts with various substrate proteins, regulating numerous cell physiological or pathological mechanisms. It exerts functions such as anti-inflammatory, anti-fibrotic, and cytoprotective effects by modulating post-translational modifications of crucial proteins within cells. HDAC6 is also overexpressed in ADPKD, fibrotic diseases, neurodegenerative disorders, and cancers, highlighting its significant role in various diseases.

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